Help shape the future of TMA care.
Research can help investigators understand how TMA presents, how it changes over time, and which approaches may improve outcomes. Participation is always voluntary.
What am I being asked to do?
Each study should clearly explain visits, surveys, samples, records, or other activities before you decide whether to participate.
Will my information be private?
Research teams should explain how information is protected and what may be shared for approved research.
Can I change my mind?
Study-specific consent materials explain your rights, including whether and how you may withdraw.
USTMA studies
Availability and eligibility vary by site. Contact the study team for current information.
P200 Registry & Tissue Bank
A prospective longitudinal clinical registry and biobank supporting multicenter iTTP research across the USTMA network.
View study details →NeST — Neurologic Sequelae of iTTP
A multicenter study evaluating long-term neurologic, cognitive, quality-of-life, and patient-reported outcomes after acute iTTP.
View study details →R300 — Retrospective Pediatric TTP Registry
A retrospective registry studying pediatric immune and congenital TTP using clinical and treatment data from participating institutions.
View study details →R400 — Complement-Mediated TMA Study
A multicenter retrospective study focused on presentation, management, and short- and long-term outcomes in complement-mediated TMA.
View study details →R100 — Retrospective Adult iTTP Registry
A completed retrospective adult iTTP registry that serves as a resource for approved secondary analyses and publications.
View study details →Prospective TMA Registry
A prospective research concept designed to collect standardized longitudinal clinical data and biospecimens across TMA populations.
View study details →